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The Molecular Biology Core Facility is located
on the second floor of the Cannon Research Center on the Carolinas Medical
Center (CMC) campus. This facility is
equipped with state-of-the-art equipment, including:
- CCD cameras
- LS-3000 Fuji imager
- Phosphoimager BAS 1500
- ABI 310 DNA sequencer
- ABI Prism 7000 real time PCR
machine
The Molecular Core staff consists of an
MD/PhD Medical Director, PhD Molecular Geneticist Manager, five experienced
technicians, and two PhD collaborators.
Our facility provides services such as
nucleic acid extraction, microarray sample preparation, cloning and sequencing,
PCR, RT-PCR and real time PCR, Northern, and Western blotting techniques. The
facility also hosts related projects of CMC residents, OB/GYN Research,
Pediatric Genetics Research, and Urology Research.
The endocrinology and gynecological
oncology divisions of OB/GYN have been involved with several studies in the
field of endometrial and ovarian cancer in collaboration with the Molecular
Biology Core Facility. Several publications have resulted from these studies and
have lead to the establishment of women's health research endowments from local
sources.
Pediatric Genetics Research involves
studies in the field of human genetics, particularly Angelman syndrome and
Prader-Willi Syndrome, and has resulted in some major publications. McKay
Urology utilizes the facility for their prostate cancer related studies. Their
activities have also produced several publications.
The state-of-the art
Affymetrix Microarray Core
Facility serves as part of the Genomic Consortium of
Charlotte and is affiliated with the Molecular Biology Core Facility. The Mass
Spectrometry Facility serves as the Proteomic Consortium of Charlotte and is
also a part of the Molecular Biology Core Facility. This facility will be
managed by a PhD Mass Spectrometry Specialist. The Molecular Biology Core
Facility has collaborated closely with UNC-Charlotte faculty and students in the
past few years.
Contact Information
Cannon Research
Administration
Phone: 704-355-3972
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